As far as i know, search api won’t do substring matching. One way around this would be to build up a vocabulary of #AwesomeSomething, #AwesomeSomethingelse, #AwesomeEtc. and query for those.
Or listen to the public sample stream and do your own matching for #awesome[^\s]+ to discover new hashtags you might have missed (but this is more of an opportunistic thing since sample stream is only 1% for all tweets)