Get tweets on only selected users


We need only latest tweets from selected accounts in real time.
Is it possible to get tweets of selected twitter users using streaming API ?


Yes. create a stream with a filter. Note that if you use a track parameter, you’re limited to number of terms for a single stream.

If you are doing this for business purposes on behalf of a client, I would consider Gnip PowerTrack, as you can create multiple streams. (Note that Gnip is a paid product.)