From my basic tests, it seems that promotable tweets can be deleted, however they still remain associated with a line item, and you have to manually disassociate them. This seems like a problematic thing on Twitter’s part as i don’t know what a line_item will display when the tweet is deleted and no longer available.
Essentially the line_item has a broken association which shouldn’t hold and should be cleaned up automatically behind the scenes.
Would like more information on this from Twitter’s team.