Application marked as spam in mistake



I created a application and was using the APIs to post tweets when someone mentioned the account in a tweet.
After a while, it went viral and there was a rush in traffic. Twitter spam detectors marked it as spam and started returning error code 226 for a while. The error was later resolved. However, now when a post is made, in reply to a tweet, it does not generate any push/in-app notification. Any activity related notification from the account is not generating notification.
Who and where can this issue be addressed?